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Common side effects of Adderall can include: lack of appetite dry mouth trouble sleeping headache stomach pain constipation nausea weight loss anxiety dizziness The following are examples of serious side effects and their symptoms: heart problems including rapid heartbeat, high blood pressure , heart attack, and stroke depression impaired or delusional thinking hallucinations blurred vision agitated or aggressive behavior irritability severe allergic reaction muscle breakdown called rhabdomyolysis Long-term use of Adderall , when misused or abused, can lead to physical and psychological dependence. Inappropriate use can result in a variety of serious side effects, including: fatigue severe insomnia or trouble sleeping moodiness or irritability depression skin disorders heart damage symptoms of psychosis such as hallucinations and aggression anorexia and unwanted weight loss