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You may have breathing issues or withdrawal symptoms if you start or stop taking certain other drugs. Tell your doctor if you also use antibiotics, antifungal medication , heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C. Opioids can interact with many other medicines and cause dangerous side effects or death. Make sure to tell your doctor if you also use: other narcotic medication - opioid pain medicine or prescription cough medicine sedatives like Valium, including diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax , and others drugs that make you sleepy or slow your breathing - a sleeping pill, muscle relaxer, tranquilizer, antidepressant, or antipsychotic medicine drugs that affect levels of serotonin in your body - a stimulant or medicine for depression , Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting

Do not use methadone if you are allergic to it, or if you have: breathing problems or severe asthma a blockage in your stomach or intestines To make sure methadone is safe for you, tell your doctor if you have ever had: breathing problems, sleep apnea liver or kidney disease brain tumor, a head injury, or seizures heart problems, long QT syndrome (in you or a family member) alcohol or drug addiction, or mental illness urination problems problems with your gallbladder, pancreas, or thyroid Methadone can cause a fatal heart rhythm disorder. If you have a headache with chest pain, severe dizziness, or fast or pounding heartbeats, call your doctor right away. Your doctor may check your heart function during treatment. If you use opioid medications while pregnant, your baby may become dependent on the drug. This can cause fatal withdrawal symptoms in the baby after birth. Babies born dependent on opioids may require medical care for several weeks. Do not breastfeed. Methadone can enter...